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This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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Fmoc-(S)-3-Amino-3-(3,5-dimethoxy-phenyl)-propionic acid is a Amino Acid reagent (Subcategory: Beta AA) sold by WuXi TIDES. Offered in 10 g. Store at 4 °C. SDS available for reference.
Specifications - CAS: 501015-38-9 - MDL: MFCD03427984 - InChIKey: SPQPUHLSWLGXSO-DEOSSOPVSA-N - Molecular Weight: 447.487 - Molecular Formula: C26H25NO6 - Purity: ≥95% - Container Type: 60 mL HDPE - Pack Size: 10 g - Net Weight: 10 g - Gross Weight: 25 g - Commodity Code: 29242970 - Country Of Origin: China - IUPAC: (S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(3,5-dimethoxyphenyl)propanoic acid - SMILES: COC1=CC(OC)=CC([C@H](CC(O)=O)NC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)=C1
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Internal Ctrl Lentivirus is a transcription factor reporter lentiviral vector designed to monitor Farnesoid X receptor pathway in living cells This construct delivers a Renilla Luc reporter cassette together with a Blasticidin selection marker for generation of stable cell pools The vector is provided as a ready to use Lentivirus preparation pseudotyped with VSV-G for efficient gene delivery and stable genomic integration Each vial provides a nominal titer of 2x10E6 transducing units TU Typical applications include Monitor FXR pathway activity The fluorescent reporter enables convenient readout using flow cytometry fluorescence microscopy etc The system is suitable for use with Human/mouse and can support assay development high content screening and mechanism of action studies This product is intended for research use only and is not for diagnostic or therapeutic procedures
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